Hi
I do not think that having adsense on your site would reduce your rankings, from a business point of view Google would want sites displaying adsense to be at the top of the results, it means more revenue for them.
My thought on your lack of position for some keywords is that if you get an article on “homeowner loans” you think to yourself, that will pay well in adsense so I will optimise the pages, fair enough its how you make your money, but the chances are that the person who wrote the initial “homeowner loans” article is also aiming to get to top of the rankings, they probably have a site dedicated to the term and lots of relevant links as well as the links from the article they have written, so it is just more competition for you in an already crowded market.
However when you get an article around an unpopular keyword and just do your standard optimisation you rank well because of a lack of competition.
Well just my opinion and hope it gets you thinking.
Sean
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