I also run POP THIS! for IE. Nothing wrong with two popup blockers, PopThis! is weightless.
And get SPYBOT S & D and do a good cleaning!
This is a great page I found, it has a scan for spyware - that also links to a Oakely-doakely site for info on that stuff.
http://factor1.net/external/dnld.html
Spybot, when you install it, click the 'Check for updates'
Then unclick the "Languages" download part, then look right where it asks you to download updates, there is little 'dropdown box - select another site to download from! The first one bites.
Then 'Check for problems', it won't be able to 'Fix all the selected problens, do you want to run ... at next startup...= YES.
Then when all that is done, check for protections, Immunize, select 'notify me when blocking downloads (You will see just how many sites try to download crap without you being aware).
I love that option, I was shocked !
Finally, lock the 'Internet Options' from being accessed from inside IE, it stops browser highjackers from changing your home page to "http:/www.pornXXXXXX.com/I_just_put_script_in your computer/haha.html?=7^%02$?"
Just don't read the last two lines here, I am on sleep deprivation research and ..what werewe talking about...