I have a few questions for you.

1. Do you want to sell anything?
Yes - What do you have a interested in? Find a drop shipper or buy a drop shippers list.
No - Ad-sense, Affiliates, Providing Services maybe best.

2. Is this for you or for your wife/hubby?
Wife/hubby - Make sure he/she has the time, motivation and wants to do it.
You - Make sure you have the time and motivation

3. How much time do you plain on spending on this?
none - Most people believe "put up a site and make money" As you may know this is not the case.
Depends on other answers. but a range is 2-10+ hours a day.

4. How much money do you wish to outlay to start?
Again depends on other answers can range from 0 - 1500+. Things people do not think of but may need
Gateway, Hosting, Shopping Cart, Merchant Account, Fax machine, New Phone Line, 800 Number. Just to name a few

5. How long do you think it will take before you start making money?
Can take from a month to 6 months or more before a profit is made.

these are just things to think about.

It is not for everyone but if you still want to do it then go for it.