It all depends on the countries you´re targeting. Inglish I guess is the usa, so a .com domain is fine, and you probably host in the usa, so that's fine too. As far as I know the italian language is only practical in Italy, unless you´re trying to target people in the usa for italian-english translations. If you´re targeting the italian language, I guess it doesn't really matter much, though I would go for a .it domain.

The spanish language is a completely different matter. What countries are you targeting? If it is spanish for the spanish speakers in the usa, you´re fine but if you´re targeting other countries you need to have a site for each country. Spanish is spoken in so many countries it would be impossible for a search engine to give useful results in each country without looking at domain names and in many cases also the location of the server.

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