Thanks for all the thoughtful replies. I publish travel books for a living. The sites I create are travel-related and are basically an effort to increase awareness of the titles I publish. That and earn some revenue through GoogleAds and affiliate programs.

I've been experimenting with various CMS packages such as Geeklog, Drupal, Joomla, Mambo, etc. I've used Geeklog for one of my non-business sites and am pleased with it. I've been experimenting with Drupal for an upcoming business-related site and am impressed with it so far. I think I also need to take another serious look at Mambo and Joomla.

The stumbling block I usually run in to is customizing the site's look. I know only basic CSS (customizing a table-less site such as what Drupal uses is intimidating) and just about nothing of PHP and MySQL.

I suppose I was looking for opinions that would convince me it's time to delve into developing CMS sites and learning CSS, PHP, etc.