Interesting topic this. So, off topic links might not be favourable, but, take the case of a local community website that has multiple outbound links, even google adwords!
The topic of the website might be Smallbury in Kent with links to all manner of items! From the local church website, the various local shop and business websites all the way to links to online banks, the TV listings pages, energy companies, something that interests the webmaster - their blog! - you name it. All with a local / national relevance, most potentially off topic.
regards
Simon
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